WebApr 7, 2024 · Bipolar androgen therapy (BAT) is a new treatment concept for men whose prostate cancer is resistant to standard hormone-blocking therapy. Here the authors review results of clinical studies that were performed to test BAT in asymptomatic men with castration-resistant prostate cancer. WebApr 11, 2024 · Bipolar androgen therapy (BAT) is a new endocrinologic treatment for castration-resistant prostate cancer (CRPC) that can restore some patients’ sensitivity to drugs such as abiraterone (Abi) and enzalutamide (Enz). We performed a meta-analysis using STATA16. Sensitivity analyses were performed by examining the effects of …
Bipolar androgen therapy in prostate cancer: Current …
WebAug 1, 2024 · The bipolar androgen therapy is an under-investigation treatment that consists in periodical oscillation between castration levels and supraphysiological levels … WebApr 11, 2024 · Inhibition of androgen receptor (AR) signaling has been the mainstay of treatment of advanced prostate cancer (PCa) for the past 80 years. Combination and sequential AR-inhibiting therapies are highly effective palliative therapy, but they are not curative. All patients eventually develop resistance ... dustless hardwood floor refinishing nj
2024 Prostate Cancer Highlight - Bipolar Androgen Therapy: …
WebJan 1, 2015 · Introduction. The discovery by Dr. Charles Huggins in 1941 of the remarkable palliative benefit of androgen deprivation therapy (ADT) via surgical castration or estrogen therapy in men with symptomatic, advanced prostate cancer was a transformative event in the history of medicine (1,2).Over the ensuing 70 years, ADT has remained the mainstay … WebIn one embodiment, a prostate cancer patient can be treated with several novel approaches to bipolar androgen therapy. According to various embodiments, a combination of external beam radiation with bipolar androgen therapy can be used. According to various embodiments, one or more of intravenous injection, transdermal … WebDec 17, 2012 · Men with castration-resistant prostate cancer will initiate androgen deprivation therapy (ADT) with an LHRH agonist (e.g. goserelin or leuprolide) for a total … dustless floor refinishers near me