Cdkn2aip p53

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August undefined, 2024

WebMar 21, 2024 · Interacts with CDKN2AIP and E4F1. Interacts with CDK5RAP3 and MDM2; form a ternary complex involved in regulation of p53/TP53 (PubMed:16173922). Interacts with NOP53; the interaction is … WebThe two gene products of the CDKN2A gene, p16 and p19ARF, have recently been linked to each of two major tumour suppressor pathways in human carcinogenesis, the RB1 …

CDKN2AIP - CDKN2A-interacting protein - Function

WebCDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent … drogasil vila aviacao bauru

55602 - Gene ResultCDKN2AIP CDKN2A interacting protein [ (human)]

WebFig. 1 MiR-126 is essential for liver regeneration through inhibiting the Cdkn2aip-p53 pathway. a Relative expression of miR-126 in the perfusd hepatoctes before and after PH at different time points. WebMay 25, 2024 · The results showed that CDKN2AIP is highly expressed in normal testis samples, and is significantly suppressed in testicular seminoma clinical samples and cell line model. Up-regulation of CDKN2AIP is significantly associated with the inhibition of testicular seminoma tumor growth and the increase of cell senescence and apoptosis. WebCDKN2AIP Antibody - Cat. #: CSB-PA696531 CSB-PA696531. Regular price $328.00 USD Sale price $328.00 USD Regular price droga skuola.net

CDKN2AIP Gene - GeneCards CARF Protein CARF …

Webof p53-HDM2-p21 pathway [19]. Interestingly, our recent work found that CDKN2AIP is expressed in almost all human tissues but highest in testis, where its expression was associated with testicular tumor suppression. How-ever, it remains elusive whether Cdkn2aip has a specic role in spermatogenesis. To decipher the biological importance … WebThe Township of Fawn Creek is located in Montgomery County, Kansas, United States. The place is catalogued as Civil by the U.S. Board on Geographic Names and its elevation … drogas kupona kodsWebCoexpression of CARF and/or p14 (ARF) reduced colony number in U2OS cells in an additive manner. Hasan et al. (2002) concluded that CARF is a novel regulator of the p19 … drogas la rebaja bucaramanga provenza

"WebRegulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence. The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is … " - Cdkn2aip p53

Cdkn2aip p53

The CDKN2AIP gene and its putative association with …

WebInvitrogen Anti-CDKN2AIP Polyclonal, Catalog # PA5-41870. Tested in Western Blot (WB) and Immunohistochemistry (IHC) applications. ... The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2. For Research Use Only. Not for use in diagnostic procedures. Not for resale without express … WebIn the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2. ... CDKN2AIP; RGD1305302 UniProt ID: (Human) Q9NXV6, (Mouse) Q8BI72, (Rat) Q5U2X0. Entrez Gene ID: (Human) 55602, (Mouse) 70925, (Rat) 306455. …

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WebAug 22, 2024 · Cdkn2aip-/-mice exhibited multiple sperm head defects accompanied by age dependent germ cell loss that might be result of protamine replacement failure and impaired SUN1 expression. Loss of Cdkn2aip expression in male mice resulted in synapsis failure in 19% of all spermatocytes and increased apoptosis due to damaged DNA double-strand … WebMay 11, 2024 · CARF (Collaborator of ARF)/CDKN2AIP was discovered as a novel ARF-binding protein. It has been established as an essential cell …

WebCDKN2AIP: Full Name: CDKN2A Interacting Protein: Background: The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found … WebCDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of ...

WebJun 27, 2014 · Collaborator of ARF (CARF) has been shown to directly bind to and regulate p53, a central protein that controls tumor suppression via cellular senescence and … WebAug 12, 2016 · A couple who say that a company has registered their home as the position of more than 600 million IP addresses are suing the company for $75,000. James and …

WebInvitrogen Anti-CDKN2AIP Polyclonal, Catalog # PA5-66460. Tested in Immunocytochemistry (ICC/IF) applications. This antibody reacts with Human samples. Supplied as 100 µL purified antibody (0.2 mg/mL).

WebSeveral molecules in the DNA damage/checkpoint signaling pathway, including CHEK1, CARF (CDKN2AIP), p53, GADD45A, and p21 (CDKN1A) exhibit robust recruitment of BCL6 . ChIP-seq was not informative for ARF, because the JURL CML cells studied carry biallelic deletions at 9p21, including the CDKN2A locus . rapido uhf voronWebCDKN2AIP: CDKN2A-interacting protein; Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence; Belongs to the CARF family (580 aa) ... Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional … rapid output g-zeroWebMar 21, 2024 · GeneCards Summary for CDKN2AIP Gene. CDKN2AIP (CDKN2A Interacting Protein) is a Protein Coding gene. Diseases associated with CDKN2AIP … rapido vouwcaravanWebActivates p53/TP53 by CDKN2A-dependent and CDKN2A-independent pathways. Tissue specificity. Ubiquitously expressed. Sequence similarities. ... All lanes : Anti-CDKN2AIP … drogas la rebaja facatativaWebNational Center for Biotechnology Information rapido wilma svartWebApr 14, 2024 · Recently Concluded Data & Programmatic Insider Summit March 22 - 25, 2024, Scottsdale Digital OOH Insider Summit February 19 - 22, 2024, La Jolla rapidough game ukWebThe protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, … rapidovac