WebFeb 10, 2024 · If EDTA-mediated platelet clumping is suspected, perform a repeat platelet count using a different anticoagulant (eg, sodium citrate, heparin); recheck platelet count as soon as possible if platelet measurement is uninterpretable; hold inotersen therapy until an acceptable platelet count is confirmed with an interpretable blood … WebSep 1, 2010 · For the specific diagnosis of EDTA-induced thrombocytopenia, follow these steps: Collect the blood specimen in an EDTA-containing tube. Perform a platelet count at time 0. Repeat the …

Cell Counter‒Related Abnormalities - academia.edu

WebSample collection. Blood for hematologic testing must be collected into an anticoagulant, preferably EDTA (purple top tube). Blood smears should be made at the time of collection to minimize storage-associated changes, which invariably occur. Venipuncture should be minimally traumatic to minimize platelet activation and should be done using a ... WebThe EDTA-induced pseudothrombocytopenia is mediated by autoantibodies of IgG, IgM, and IgA subclasses directed at an epitope on glycoprotein IIb. This epitope is normally … finding someone through cell phone number

Platelet clump - American Society of Hematology

WebThe first thing is that the blood sample needs to be repeated, some problems with sample collection and storage may lead to clumping. The presence of large and giant platelets can suggest an underlying problem and this would need to be confirmed by additional testing. WebPlatelet Clumps and Satellitism. Platelet satellitism is a phenomenon that can occur in vitro when a blood sample is collected in an EDTA anticoagulant tube. Platelets adhere to neutrophils by an antibody … WebA small whole blood clot or very small fibrin clots in the EDTA anticoagulated specimen will usually be associated with clumping of platelets on the slide, and with a false low … finding someone\\u0027s location