Webjbx.sagepub.com Original Research Introduction High-throughput screening (HTS) experiments have been used extensively in drug discovery initiatives, but they also have been applied to explore alternative targets and diseases with less commercial interest.1 Remarkably, recent advances in robotics and miniaturization of biological assays have led WebMori et al. 422 www.sbsonline.org Journal of Biomolecular Screening 14(4); 2009 At a measuring time of 1.5 s, the IC 50 value of CsA was determined to be 11 nM (Fig. 2B).On the other hand, the reac-

A High-Throughput Cell-Based Gaussia Luciferase Reporter Assay …

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Using Weighted Entropy to Rank Chemicals

Webhttp://jbx.sagepub.com Introduction High-Content Landscape High-throughput screening of chemical libraries against predefined targets is an established method to generate hits … WebToggle navigation. Access. Login Webjbx.sagepub.com Original Research Introduction According to the World Health Organization (WHO), the parasites responsible for causing malaria—Plasmodium fal-ciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae—infect up to 500 million people per year and result in an estimated 650,000 fatalities.1 Current cabinet around air intake